Module 5 Acids, Bases, and Solubility Equilibrium

 

CHEM-1312 M5L1 Explore: Acid-Base Theory and Calculations

Welcome to Module 5, where we explore one of the most fundamental and widely applicable areas of chemistry: acid-base chemistry. This lesson establishes the theoretical foundation and computational skills you'll need to understand acid-base behavior in both laboratory and biological systems.

In this lesson, you'll master two essential learning objectives:

We begin with Brønsted-Lowry theory—the proton transfer model that explains most aqueous acid-base reactions—before expanding to Lewis theory, which provides a broader electron-pair framework. You'll then develop quantitative skills through pH calculations, starting with straightforward strong acid/base problems and progressing to more complex weak acid equilibrium systems.

Why This Matters: Acid-base chemistry is critical for understanding biochemical processes (blood pH regulation, enzyme function), environmental science (ocean acidification, acid rain), analytical chemistry (titrations, buffer preparation), and pharmaceutical applications (drug solubility, delivery mechanisms). The concepts and calculations you master here form the foundation for advanced topics in buffers, titrations, and solubility equilibria.

How to Succeed: Watch all 11 video segments carefully, practice the interactive activities immediately after each section, and work through the calculation problems step-by-step. Don't skip the guided solutions—understanding the problem-solving process is as important as getting the right answer.

 

Module Competencies

A ★ indicates that this page contains an activity related to that LO.

CC5.1 Compare the properties of acid and bases to determine strength and solubility

★ LO5.1.1 Apply acid-base theories (Brønsted, Lewis) to identify conjugate pairs

★ LO5.1.2 Calculate pH and pOH for strong and weak acid/base solutions

LO5.1.3 Analyze buffer systems and calculate pH changes

LO5.1.3 Analyze buffer systems and calculate pH changes

LO5.1.4 Interpret acid-base titration curves and select indicators

LO5.1.5 Apply solubility principles to predict precipitation

LO5.1.6 Predict pH effects on solubility and complex ion formation

 

Overview

What You Will Learn

Foundation Theory

  • Brønsted-Lowry Acid-Base Theory
    • Review and extend Brønsted's definitions of acids and bases in terms of proton transfer and conjugate acid-base pairs. (15.1)
  • The Acid-Base Properties of Water
    • Examine water's amphoteric nature and define the ion-product constant for autoionization of water to give H⁺ and OH⁻ ions. (15.2)

pH and Equilibrium Concepts

  • pH—A Measure of Acidity
    • Define pH as a measure of acidity and introduce the pOH scale. Understand how acidity depends on relative concentrations of H⁺ and OH⁻ ions. (15.3)
  • Strength of Acids and Bases
    • Classify acids and bases as strong or weak based on their extent of ionization in solution and understand ionization constants. (15.4)
  • Weak Acids and Acid Ionization Constants
    • Calculate the pH of weak acid solutions from concentration and ionization constant using equilibrium principles. (15.5)
  • Weak Bases and Base Ionization Constants
    • Perform similar calculations for weak bases and derive the relationship between acid and base ionization constants of conjugate pairs. (15.6 and 15.7)

Applications and Advanced Topics

  • Metal Cations as Weak Acids
    • Understand how metal cations act as acids through hydrolysis reactions and calculate pH of acidic salt solutions. (15.10)
  • Percent Ionization
    • Calculate percent ionization for weak acids and understand the relationship between concentration and ionization extent. (15.5)
  • Weak Base Equilibria
    • Apply equilibrium principles to weak base systems and understand Ka/Kb relationships for conjugate pairs. (15.6-15.7)
  • Diprotic and Polyprotic Acids
    • Study polyprotic acid systems with stepwise ionization, multiple Ka values, and pH calculations for complex systems. (15.8)
  • Molecular Structure and Acid Strength
    • Explore the relationship between molecular structure and acid strength, including binary acid trends and periodic effects. (15.9)
  • Lewis Acids and Bases
    • Extend acid-base theory to electron pair acceptors (Lewis acids) and donors (Lewis bases), including complex ion formation. (15.12)

What to Read

Overby/Chang: Chemistry, 14th Ed. - Chapter 15: Complete Chapter (15.1-15.12)

 

Foundation Theory

The tabs to the left indicate you have two videos to watch.

Acids and Bases Introduction

Time: 4:25 min.

Topics: Brønsted-Lowry acid-base theory, proton transfer, conjugate acid-base pairs, amphoteric substances, relative acid-base strength relationships

 

Acids and Bases: Properties of Water

Time: 3:45 min.

Topics: Amphoteric nature of water, auto-ionization of water, ion product constant (Kw), relationship between [H3O+] and [OH-] in aqueous solutions

 

 

Practice & Apply: Brønsted-Lowry Conjugate Pair Identification

Apply LO5.1.1: Use your understanding of Brønsted-Lowry acid-base theory from the videos above to identify conjugate acid-base pairs. Remember: a conjugate acid-base pair differs by exactly one proton (H⁺). Note: You'll practice Lewis acid-base pairs later in this lesson after learning Lewis theory.

Match Brønsted-Lowry Conjugate Acid-Base Pairs

Click to match each acid with its conjugate base. Each pair differs by exactly one H⁺ ion.

Acids & Bases to Match
HCl (hydrochloric acid)
Cl⁻ (chloride ion)
H₂O (water acting as acid)
OH⁻ (hydroxide ion)
H₃O⁺ (hydronium ion)
H₂O (water acting as base)
NH₄⁺ (ammonium ion)
NH₃ (ammonia)
CH₃COOH (acetic acid)
CH₃COO⁻ (acetate ion)
HNO₃ (nitric acid)
NO₃⁻ (nitrate ion)
Key Concepts to Remember:
  • Conjugate Pairs: Always differ by exactly one H⁺ (proton)
  • Water's Dual Role: Can act as both acid (donates H⁺) and base (accepts H⁺)
  • Strong vs Weak: Both strong and weak acids/bases form conjugate pairs
  • Brønsted-Lowry Definition: Acids donate protons, bases accept protons

 

pH and Equilibrium Concepts

The tabs to the left indicate you have four videos to watch.

pH: Measuring Acidity

pH: Measuring Acidity

Time: 4:20 min.

Topics: pH definition and scale, relationship between [H3O+] and pH, acidic vs basic vs neutral solutions, antilog calculations for concentration

 

pOH Calculations

pOH Calculations

Time: 2:35 min.

Topics: pOH definition, relationship between pH and pOH, pKw calculations, hydroxide ion concentration calculations

 

pK, pKa, and pKb

pK, pKa, and pKb

Time: 3:10 min.

Topics: pK calculations, relationship between Ka and pKa, Kb and pKb, logarithmic relationships in acid-base chemistry

 

Strength of Acids and Bases

Strength of Acids and Bases

Time: 3:15 min.

Topics: Ionization constants (Ka/Kb), strong vs weak acids, acid/base dissociation, relationship between acid strength and conjugate base strength

 

 

Practice & Apply: pH/pOH Calculations

Apply LO5.1.2: Use the calculation methods from the videos above to solve pH and pOH problems. Problems progress from basic to advanced difficulty. Try each problem before checking the answer!

PROBLEM 1 - BASIC Calculate the pH of a 0.010 M HCl solution.

Answer & Step-by-Step Solution

Answer: pH = 2.00

Not what you got? Study this walk-through to understand where you went wrong.

Step 1: Recognize that HCl is a strong acid that completely ionizes: HCl → H⁺ + Cl⁻

Step 2: For strong acids, [H⁺] = initial acid concentration = 0.010 M

Step 3: Calculate pH using pH = -log[H⁺] = -log(0.010) = -log(1.0 × 10⁻²) = 2.00

PROBLEM 2 - BASIC Calculate the pH and pOH of a 0.0050 M NaOH solution at 25°C.

Answer & Step-by-Step Solution

Answer: pOH = 2.30, pH = 11.70

Not what you got? Study this walk-through to understand where you went wrong.

Step 1: Recognize that NaOH is a strong base: NaOH → Na⁺ + OH⁻

Step 2: For strong bases, [OH⁻] = initial base concentration = 0.0050 M

Step 3: Calculate pOH: pOH = -log[OH⁻] = -log(0.0050) = -log(5.0 × 10⁻³) = 2.30

Step 4: Use pH + pOH = 14.00 at 25°C: pH = 14.00 - 2.30 = 11.70

PROBLEM 3 - INTERMEDIATE If a strong acid solution has a pH of 1.85, what is the concentration of H⁺ ions?

Answer & Step-by-Step Solution

Answer: [H⁺] = 0.014 M or 1.4 × 10⁻² M

Not what you got? Study this walk-through to understand where you went wrong.

Step 1: Start with the pH equation: pH = -log[H⁺]

Step 2: Substitute the given pH: 1.85 = -log[H⁺]

Step 3: Solve for [H⁺] using the antilog: [H⁺] = 10⁻ᵖᴴ = 10⁻¹·⁸⁵

Step 4: Calculate: [H⁺] = 0.014 M (or 1.4 × 10⁻² M in scientific notation)

PROBLEM 4 - INTERMEDIATE Acetic acid (CH₃COOH) has a pKₐ of 4.75. Calculate the Kₐ value for acetic acid.

Answer & Step-by-Step Solution

Answer: Kₐ = 1.8 × 10⁻⁵

Not what you got? Study this walk-through to understand where you went wrong.

Step 1: Recall the relationship between pKₐ and Kₐ: pKₐ = -log(Kₐ)

Step 2: Substitute the given pKₐ: 4.75 = -log(Kₐ)

Step 3: Solve for Kₐ using the antilog: Kₐ = 10⁻ᵖᴷₐ = 10⁻⁴·⁷⁵

Step 4: Calculate: Kₐ = 1.8 × 10⁻⁵

PROBLEM 5 - ADVANCED Calculate the pH of a 0.10 M solution of formic acid (HCOOH) given that Kₐ = 1.8 × 10⁻⁴.

Answer & Step-by-Step Solution

Answer: pH = 2.37

Not what you got? Study this walk-through to understand where you went wrong.

Step 1: Set up the ICE table for HCOOH ⇌ H⁺ + HCOO⁻:

Initial: [HCOOH] = 0.10 M, [H⁺] = 0, [HCOO⁻] = 0

Change: [HCOOH] = -x, [H⁺] = +x, [HCOO⁻] = +x

Equilibrium: [HCOOH] = 0.10-x, [H⁺] = x, [HCOO⁻] = x

Step 2: Write the Kₐ expression: Kₐ = [H⁺][HCOO⁻]/[HCOOH] = x²/(0.10-x)

Step 3: Substitute Kₐ: 1.8 × 10⁻⁴ = x²/(0.10-x)

Step 4: Check if x << 0.10: If so, approximate as x²/0.10 = 1.8 × 10⁻⁴

Step 5: Solve: x² = 1.8 × 10⁻⁵, so x = 4.24 × 10⁻³ M = [H⁺]

Step 6: Calculate pH: pH = -log(4.24 × 10⁻³) = 2.37

PROBLEM 6 - ADVANCED At 25°C, if [OH⁻] = 2.5 × 10⁻³ M, calculate [H⁺], pH, and pOH. Use Kw = 1.0 × 10⁻¹⁴.

Answer & Step-by-Step Solution

Answer: [H⁺] = 4.0 × 10⁻¹² M, pH = 11.40, pOH = 2.60

Not what you got? Study this walk-through to understand where you went wrong.

Step 1: Use the water autoionization constant: Kw = [H⁺][OH⁻] = 1.0 × 10⁻¹⁴

Step 2: Solve for [H⁺]: [H⁺] = Kw/[OH⁻] = (1.0 × 10⁻¹⁴)/(2.5 × 10⁻³)

Step 3: Calculate [H⁺]: [H⁺] = 4.0 × 10⁻¹² M

Step 4: Calculate pOH: pOH = -log[OH⁻] = -log(2.5 × 10⁻³) = 2.60

Step 5: Calculate pH: pH = -log[H⁺] = -log(4.0 × 10⁻¹²) = 11.40

Step 6: Verify: pH + pOH = 11.40 + 2.60 = 14.00 ✓

Skill Development Summary

Problems 1-2: Master basic strong acid/base pH and pOH calculations

Problems 3-4: Practice converting between pH/pOH and concentrations, pK relationships

Problems 5-6: Apply equilibrium calculations to weak acids and Kw relationships

 

Applications And Advanced Topics

Do not let the title fool you. These videos are required and do contain content, not just additional examples. The tabs to the left indicate you have six videos to watch.

Cations as Weak Acids

Cations as Weak Acids

Time: 3:05 min.

Topics: Metal cations acting as acids, hydrolysis reactions, acidic cations in aqueous solution, salt pH calculations

 

Percent Ionization

Percent Ionization

Time: 2:55 min.

Topics: Percent ionization calculations for weak acids, relationship between concentration and percent ionization, practical applications

 

Weak Bases and Base Ionization Constant

Weak Bases and Base Ionization Constant

Time: 3:30 min.

Topics: Weak base equilibria, Kb calculations, relationship between Ka and Kb for conjugate pairs, base ionization calculations

 

Diprotic and Triprotic Acids

Diprotic and Triprotic Acids

Time: 4:15 min.

Topics: Polyprotic acid systems, stepwise ionization, multiple Ka values, pH calculations for polyprotic systems

 

Strength of Binary Acids

Strength of Binary Acids

Time: 2:50 min.

Topics: Binary acid trends, relationship between molecular structure and acid strength, periodic trends affecting acidity

 

Lewis Acids and Bases Theory

Lewis Acids and Bases Theory

Time: 0:00 min.

Topics: Lewis Theory Definition & Concepts, Common Lewis Acids & Bases Examples, Lewis Acid-Base Reaction Mechanism, Practical Applications & LO5.1.1 Connection,

🎬 In-Development - Lewis Acids and Bases Theory

📹 VIDEO PRODUCTION REQUIRED

Time Target: 4-5 minutes | Priority: HIGH | Chapter 15.12 Coverage

🎯 Essential Content Guidelines for Video Production:
1. Lewis Theory Definition & Concepts (1.5 min)
  • Lewis Acid Definition: Electron pair acceptor (emphasize electron deficiency)
  • Lewis Base Definition: Electron pair donor (emphasize lone pair availability)
  • Key Distinction: No proton transfer required (vs Brønsted-Lowry theory)
  • Visual Focus: Electron movement arrows, orbital diagrams showing electron pairs
2. Common Lewis Acids & Bases Examples (1.5 min)
  • Lewis Acids: BF₃, AlCl₃, metal cations (Fe³⁺, Cu²⁺), H⁺
  • Lewis Bases: NH₃, H₂O, OH⁻, halide ions (F⁻, Cl⁻)
  • Visual Emphasis: Show electron dot structures highlighting lone pairs and empty orbitals
  • Connection: Explain how Brønsted acids/bases are subset of Lewis acids/bases
3. Lewis Acid-Base Reaction Mechanism (1.5 min)
  • Coordinate Covalent Bond Formation: Show electron pair donation process
  • Example Reaction: NH₃ + BF₃ → NH₃BF₃ (show complete mechanism)
  • Curved Arrow Notation: Demonstrate electron movement from base to acid
  • Product Analysis: Identify adduct formation and bonding changes
4. Practical Applications & LO5.1.1 Connection (0.5 min)
  • Complex Ion Formation: Metal-ligand interactions in coordination chemistry
  • Catalysis Examples: Lewis acid catalysts in organic reactions
  • Assessment Preparation: "Students will apply Lewis theory to identify acid-base pairs"
🎬 Production Specifications:
  • Visual Style: Clear molecular structures with highlighted electron movements
  • Pacing: Deliberate speed for complex electron movement concepts
  • Graphics Required: Lewis structures, orbital diagrams, curved arrow mechanisms
  • Animation Needs: Electron pair movement, bond formation sequences
  • Assessment Bridge: Conclude with examples that link to LO5.1.1 application activities
⚠️ Critical Coverage Gaps Addressed:
  • LO5.1.1 Requirement: "Apply acid-base theories (Brønsted, Lewis)" - currently missing Lewis coverage
  • Chapter 15.12 Alignment: Complete textbook section coverage
  • Theory Integration: Connect Lewis theory to existing Brønsted-Lowry foundation
  • Application Preparation: Enable interactive conjugate pair identification for Lewis systems

 

 

Practice & Apply: Advanced Acid-Base Concepts

Apply LO5.1.1: Master advanced acid-base concepts including Lewis theory, polyprotic systems, and structural effects. These activities reinforce concepts from videos 007-011 and prepare you for Lewis theory applications.

Lewis Acid-Base Pair Identification

Apply Lewis theory to identify electron acceptors and electron donors. Remember: Lewis acids accept electron pairs, Lewis bases donate electron pairs.

Match Lewis Acid-Base Pairs

Click to match each Lewis acid with its corresponding Lewis base in these reaction examples.

Lewis Acids & Bases to Match
BF₃ (electron deficient, accepts electron pairs)
NH₃ (has lone pair, donates electrons)
Cu²⁺ (metal cation, electron acceptor)
H₂O (ligand with lone pairs)
H⁺ (proton, electron pair acceptor)
OH⁻ (has lone pairs, electron donor)
AlCl₃ (electron deficient aluminum)
Cl⁻ (chloride with lone pairs)
Fe³⁺ (metal cation, needs electrons)
CN⁻ (cyanide with lone pair)
BH₃ (borane, electron deficient)
THF (tetrahydrofuran, oxygen lone pairs)
Lewis Theory Key Points:
  • No H⁺ Transfer: Lewis theory doesn't require proton movement
  • Electron Focus: All about electron pair donation/acceptance
  • Broader Scope: Includes reactions Brønsted-Lowry cannot explain
  • Coordinate Bonds: Forms coordinate covalent bonds in products

 

Theory Comparison: Lewis vs Brønsted-Lowry

Click each card to explore how different acid-base theories apply to various chemical systems.


NH₃ + BF₃ → NH₃BF₃

Which acid-base theory explains this reaction?

Lewis Theory Only!

No proton transfer occurs. NH₃ donates electron pair to BF₃. Brønsted-Lowry cannot explain this reaction.


HCl + H₂O → H₃O⁺ + Cl⁻

Which theories explain this reaction?

Both Theories!

Brønsted-Lowry: H⁺ transfer from HCl to H₂O. Lewis: H⁺ accepts electron pair from H₂O.


Cu²⁺ + 4H₂O → [Cu(H₂O)₄]²⁺

Complex ion formation - which theory applies?

Lewis Theory Only!

Cu²⁺ accepts electron pairs from H₂O ligands. No protons involved - pure Lewis acid-base chemistry.

 

Classify Acid-Base Systems

Sort these chemical species and reactions based on their acid-base behavior. Use concepts from videos 007-011.

Sort Acid-Base Systems

Drag each item to the correct category based on its acid-base behavior.

Answer Bank
  • BF₃ + NH₃ reaction
  • Al³⁺ hydrolysis
  • H₂SO₄ ionization
  • NH₄⁺ acting as acid
  • HF binary acid
  • [Cu(H₂O)₆]²⁺ complex
Brønsted-Lowry Systems
  • H₂SO₄ ionization
  • NH₄⁺ acting as acid
  • HF binary acid
Lewis-Only Systems
  • BF₃ + NH₃ reaction
  • Al³⁺ hydrolysis
  • [Cu(H₂O)₆]²⁺ complex

 

Advanced Equilibrium Calculations

Apply concepts from videos 007-010 to solve complex acid-base problems.

ADVANCED Calculate the pH of a 0.10 M Al(NO₃)₃ solution. Ka for [Al(H₂O)₆]³⁺ = 1.4 × 10⁻⁵

Answer & Step-by-Step Solution

Answer: pH = 2.93

This applies concepts from Video 007: Cations as Weak Acids

Step 1: Recognize Al³⁺ forms hydrated complex: [Al(H₂O)₆]³⁺

Step 2: The complex acts as weak acid: [Al(H₂O)₆]³⁺ ⇌ [Al(H₂O)₅OH]²⁺ + H⁺

Step 3: Set up ICE table with [Al³⁺] = 0.10 M initially

Step 4: Ka = 1.4 × 10⁻⁵ = [H⁺]²/(0.10 - [H⁺])

Step 5: Solve: [H⁺] = 1.18 × 10⁻³ M

Step 6: pH = -log(1.18 × 10⁻³) = 2.93

 

EXPERT For 0.10 M H₂CO₃: Ka1 = 4.3 × 10⁻⁷, Ka2 = 5.6 × 10⁻¹¹. Calculate pH and [CO₃²⁻].

Answer & Step-by-Step Solution

Answer: pH = 3.67, [CO₃²⁻] = 5.6 × 10⁻¹¹ M

This applies concepts from Video 010: Diprotic and Triprotic Acids

Step 1: For polyprotic acids, first ionization dominates pH

Step 2: H₂CO₃ ⇌ H⁺ + HCO₃⁻ (use Ka1 only for pH)

Step 3: Ka1 = [H⁺][HCO₃⁻]/[H₂CO₃] = x²/(0.10-x)

Step 4: 4.3 × 10⁻⁷ = x²/0.10, so x = 2.1 × 10⁻⁴ M

Step 5: pH = -log(2.1 × 10⁻⁴) = 3.67

Step 6: For diprotic acids: [CO₃²⁻] = Ka2 = 5.6 × 10⁻¹¹ M

 

Polyprotic Acid Characteristics

Based on Video 010 content, select ALL statements that correctly describe polyprotic acids.

Select All Correct Statements

Select all characteristics that apply to polyprotic acids like H₂SO₄, H₃PO₄, and H₂CO₃.

  • Have multiple ionizable hydrogen atoms
  • Undergo stepwise ionization
  • Each step has its own Ka value
  • Ka1 > Ka2 > Ka3 (successive Ka values decrease)
  • pH is primarily determined by the first ionization
  • All hydrogen atoms ionize simultaneously
  • All Ka values are equal
  • pH depends equally on all ionization steps

 

Advanced Concepts Mastery Summary

Lewis Theory Applications:

  • Electron pair donor/acceptor identification
  • Complex ion formation mechanisms
  • Reactions beyond Brønsted-Lowry scope

Advanced Equilibrium Skills:

  • Metal cation hydrolysis calculations
  • Polyprotic acid pH determination
  • Structural effects on acidity