This site was built as a personal health tool and shared with family because several of the conditions documented here have a genetic basis. If you carry MTHFR, Celiac, or APOE variants, knowing early โ and acting on it โ is genuinely protective.
This is not a medical website and nothing here replaces your own doctor. Think of it as a well-researched starting point: what to ask about, what labs to request, and what daily choices move the needle.
๐
Currently in active recovery โ Phase 2 begins May 2026
After years of an extremely high-stress, high-screen-time job and a prolonged caregiving crisis, Tammy is stepping away from work for a minimum of three months. The primary therapeutic goal is cortisol reset โ allowing the HPA axis to down-regulate so that diet, supplements, and movement can actually work. Chronic cortisol elevation drives glucose dysregulation, gut permeability, impaired methylation, and poor sleep; no protocol overcomes a nervous system still under that load.
MTHFR C677T
Celiac Disease
APOE4 (cognitive risk)
Pre-diabetes ยท Dawn Phenomenon
Kidney Stone (oxalate)
Klebsiella UTI history
๐จโ๐ฉโ๐งโ๐ฆ Why This Matters for Our Family
Both parents carry MTHFR C677T and Celiac Disease โ both are autosomal, meaning each child has a meaningful chance of inheriting one or both. Getting tested and starting methylated B-vitamins and a strict GF diet early prevents decades of subclinical damage.
๐งฌ MTHFR C677T
Both parents carry this variant. Reduces folate processing ~40โ70%. Simple fix: methylfolate (not folic acid) + B2. Test: request MTHFR genotype + homocysteine level from your GP.
๐พ Celiac Disease
First-degree relatives have ~10% risk vs ~1% in general population. Can present silently for years. Test: tTG-IgA antibody (must be eating gluten at time of test). Do not go GF before testing.
๐ง APOE Genotype
Dad carries two APOE3 (e3/e3) โ the neutral, most common form. Mom carries one APOE4 copy. Each child has a ~50% chance of inheriting one APOE4 from Mom and will have e3/e4. Knowing early means you can start brain-protective habits in your 30sโ40s when they matter most. Test: direct-to-consumer (23andMe) or ask your GP.
๐
Pre-diabetes / Dawn Phenomenon
MTHFR + stress + family metabolic history = higher risk. A fasting insulin + glucose (HOMA-IR) test at your annual physical is all it takes to catch this early. Reversible with diet and sleep โ much harder once A1c climbs.
๐ก The simplest first step for any family member
Ask your doctor for: tTG-IgA (Celiac) ยท Homocysteine ยท MTHFR genotype ยท Fasting insulin + glucose. Four tests. One blood draw. Enormous peace of mind โ or a very actionable early warning.
โ ๏ธ Important: Do not go gluten-free before Celiac testing
The tTG-IgA test requires active gluten exposure to detect antibodies. If you suspect Celiac, get tested first, then go GF after confirmation.